What is Trimethoprim?

Trimethoprim belongs to the class of chemotherapeutic agents known as dihydrofolate reductase inhibitors. It is an antibiotic used to treat various bacterial infections such as urinary tract infections, traveler's diarrhea, respiratory and middle ear infections. It works by stopping the growth of bacteria.

This antibiotic treats only bacterial infections. It will not work for viral infections (such as the common cold or flu). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.

Trimethoprim was formerly marketed by GlaxoWellcome under trade names including Proloprim®, Monotrim® and Triprim®. Today, however, these trade names have been licensed to various generic pharmaceutical manufacturers.

In clinical use it is often abbreviated TRI or TMP, and its common laboratory abbreviation is W.

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